Digital imaging and communication in medicine, or DICOM, is a standard of conformity used by the majority of imaging hardware (CT/CBCT) and software manufacturers for the proper handling, storing, printing, and transmitting of information in medical digital diagnostic imaging. It allows the three-dimensional imaging data obtained from different manufacturers to be used in third-party software for the visualization, surgical evaluation, and creation of CAD/CAM models and appliances. In addition, DICOM allows digital diagnostic imaging modalities to be integrated into a picture archiving and communication system (PACS). DICOM is essential in dentistry, periodontology, and endodontics as it allows a patient’s imaging data to be accurately obtained and processed in the creation of a dental restoration or procedure. The images can be distributed to the various practitioners, laboratories, and manufacturers needed to create a fully functional prosthesis or implant with the assurance that all parties involved are receiving and working from the same imaging data.